فهرست مطالب
Front Matter ....Pages i-xv
Front Matter ....Pages 1-1
Production of Phage Therapeutics and Formulations: Innovative Approaches (Maia Merabishvili, Jean-Paul Pirnay, Kilian Vogele, Danish J. Malik)....Pages 3-41
Phage Pharmacokinetics: Relationship with Administration Route (Shigenobu Matsuzaki, Jumpei Uchiyama)....Pages 43-57
Bacterial Resistance to Phage and Its Impact on Clinical Therapy (Shawna McCallin, Frank Oechslin)....Pages 59-88
Front Matter ....Pages 89-89
Phage Interaction with the Mammalian Immune System (Jonas D. Van Belleghem, Krystyna Dąbrowska, Mario Vaneechoutte, Jeremy J. Barr)....Pages 91-122
Humoral Immune Response to Phage-Based Therapeutics (Maciej Żaczek, Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Wojciech Fortuna, Paweł Rogóż et al.)....Pages 123-143
Front Matter ....Pages 145-145
How to Achieve a Good Phage Therapy Clinical Trial? (Jérôme Gabard, Patrick Jault)....Pages 147-168
Treatment and Prevention of Bacterial Infections Using Bacteriophages: Perspectives on the Renewed Interest in the United States (Randall Kincaid)....Pages 169-187
Phage Therapy in Orthopaedic Implant-Associated Infections (Paweł Rogóż, Derek F. Amanatullah, Ryszard Międzybrodzki, Robert Manasherob, Nina V. Tikunova, Beata Weber-Dąbrowska et al.)....Pages 189-211
The Use of Bacteriophages in Animal Health and Food Protection (Katarzyna Kosznik-Kwaśnicka, Gracja Topka, Aleksandra Dydecka, Agnieszka Necel, Bożena Nejman-Faleńczyk, Sylwia Bloch et al.)....Pages 213-256
Combining Bacteriophages with Other Antibacterial Agents to Combat Bacteria (Petar Knezevic, Verica Aleksic Sabo)....Pages 257-293
Phage Therapy of Infectious Biofilms: Challenges and Strategies (Luís D. R. Melo, Diana Priscila Pires, Rodrigo Monteiro, Joana Azeredo)....Pages 295-313
Front Matter ....Pages 315-315
Phage Lysins: Novel Alternative to Antibiotics (Vincent A. Fischetti)....Pages 317-334
Front Matter ....Pages 335-335
Regulatory Considerations for Bacteriophage Therapy Products (Roger D. Plaut, Scott Stibitz)....Pages 337-349
Developing Phages into Medicines for Europe (Eric Pelfrene, Zigmars Sebris, Marco Cavaleri)....Pages 351-361
Phage Therapy in Europe: Regulatory and Intellectual Property Protection Issues (Daniel De Vos, Gilbert Verbeken, Johan Quintens, Jean-Paul Pirnay)....Pages 363-377
Ethics of Phage Therapy (Jan Borysowski, Andrzej Górski)....Pages 379-385
Front Matter ....Pages 1-1
Production of Phage Therapeutics and Formulations: Innovative Approaches (Maia Merabishvili, Jean-Paul Pirnay, Kilian Vogele, Danish J. Malik)....Pages 3-41
Phage Pharmacokinetics: Relationship with Administration Route (Shigenobu Matsuzaki, Jumpei Uchiyama)....Pages 43-57
Bacterial Resistance to Phage and Its Impact on Clinical Therapy (Shawna McCallin, Frank Oechslin)....Pages 59-88
Front Matter ....Pages 89-89
Phage Interaction with the Mammalian Immune System (Jonas D. Van Belleghem, Krystyna Dąbrowska, Mario Vaneechoutte, Jeremy J. Barr)....Pages 91-122
Humoral Immune Response to Phage-Based Therapeutics (Maciej Żaczek, Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Wojciech Fortuna, Paweł Rogóż et al.)....Pages 123-143
Front Matter ....Pages 145-145
How to Achieve a Good Phage Therapy Clinical Trial? (Jérôme Gabard, Patrick Jault)....Pages 147-168
Treatment and Prevention of Bacterial Infections Using Bacteriophages: Perspectives on the Renewed Interest in the United States (Randall Kincaid)....Pages 169-187
Phage Therapy in Orthopaedic Implant-Associated Infections (Paweł Rogóż, Derek F. Amanatullah, Ryszard Międzybrodzki, Robert Manasherob, Nina V. Tikunova, Beata Weber-Dąbrowska et al.)....Pages 189-211
The Use of Bacteriophages in Animal Health and Food Protection (Katarzyna Kosznik-Kwaśnicka, Gracja Topka, Aleksandra Dydecka, Agnieszka Necel, Bożena Nejman-Faleńczyk, Sylwia Bloch et al.)....Pages 213-256
Combining Bacteriophages with Other Antibacterial Agents to Combat Bacteria (Petar Knezevic, Verica Aleksic Sabo)....Pages 257-293
Phage Therapy of Infectious Biofilms: Challenges and Strategies (Luís D. R. Melo, Diana Priscila Pires, Rodrigo Monteiro, Joana Azeredo)....Pages 295-313
Front Matter ....Pages 315-315
Phage Lysins: Novel Alternative to Antibiotics (Vincent A. Fischetti)....Pages 317-334
Front Matter ....Pages 335-335
Regulatory Considerations for Bacteriophage Therapy Products (Roger D. Plaut, Scott Stibitz)....Pages 337-349
Developing Phages into Medicines for Europe (Eric Pelfrene, Zigmars Sebris, Marco Cavaleri)....Pages 351-361
Phage Therapy in Europe: Regulatory and Intellectual Property Protection Issues (Daniel De Vos, Gilbert Verbeken, Johan Quintens, Jean-Paul Pirnay)....Pages 363-377
Ethics of Phage Therapy (Jan Borysowski, Andrzej Górski)....Pages 379-385